Past Events › Stochastics and Statistics Seminar Series

Abstract: We introduce the jackknife+, a novel method for constructing predictive confidence intervals that is robust to the distribution of the data. The jackknife+ modifies the well-known jackknife (leaveoneout cross-validation) to account for the variability in the fitted regression function when we subsample the training data. Assuming exchangeable training samples, we prove that the jackknife+ permits rigorous coverage guarantees regardless of the distribution of the data points, for any algorithm that treats the training points symmetrically (in contrast, such guarantees…

Abstract: We introduce the diffusion K-means clustering method on Riemannian submanifolds, which maximizes the within-cluster connectedness based on the diffusion distance. The diffusion K-means constructs a random walk on the similarity graph with vertices as data points randomly sampled on the manifolds and edges as similarities given by a kernel that captures the local geometry of manifolds. Thus the diffusion K-means is a multi-scale clustering tool that is suitable for data with non-linear and non-Euclidean geometric features in mixed dimensions. Given…

Abstract: Privacy-preserving data analysis has been put on a firm mathematical foundation since the introduction of differential privacy (DP) in 2006. This privacy definition, however, has some well-known weaknesses: notably, it does not tightly handle composition. This weakness has inspired several recent relaxations of differential privacy based on the Renyi divergences. We propose an alternative relaxation we term “f-DP”, which has a number of nice properties and avoids some of the difficulties associated with divergence based relaxations. First, f-DP preserves…

Abstract: Bulk sequencing of tumor DNA is a popular strategy for uncovering information about the spectrum of mutations arising in the tumor, and is often supplemented by multi-region sequencing, which provides a view of tumor heterogeneity. The statistical issues arise from the fact that bulk sequencing makes the determination of sub-clonal frequencies, and other quantities of interest, difficult. In this talk I will discuss this problem, beginning with its setting in population genetics. The data provide an estimate of the…

Abstract: Many algorithms take prohibitively long to run on modern, large data sets. But even in complex data sets, many data points may be at least partially redundant for some task of interest. So one might instead construct and use a weighted subset of the data (called a “coreset”) that is much smaller than the original dataset. Typically running algorithms on a much smaller data set will take much less computing time, but it remains to understand whether the output…

Abstract: The affinity between statistical physics and machine learning has long history, this is reflected even in the machine learning terminology that is in part adopted from physics. Current theoretical challenges and open questions about deep learning and statistical learning call for unified account of the following three ingredients: (a) the dynamics of the learning algorithm, (b) the architecture of the neural networks, and (c) the structure of the data. Most existing theories are not taking in account all of those…

Abstract: We consider the problems of learning discrete structures from network data under statistical settings. Popular examples include various block models, Z2 synchronization and mixture models. Semidefinite programming (SDP) relaxation has emerged as a versatile and robust approach to these problems. We show that despite being a relaxation, SDP achieves the optimal Bayes error rate in terms of distance to the target solution. Moreover, SDP relaxation is provably robust under the so-called semirandom model, which frustrates many existing algorithms. Our…

The claim of a ‘post-truth’ society, in which emotional responses trump balanced consideration of evidence, presents a strong challenge to those who value quantitative and scientific evidence: how can we communicate risks and unavoidable scientific uncertainty in a transparent and trustworthy way? Communication of quantifiable risks has been well-studied, leading to recommendations for using an expected frequency format. But deeper uncertainty about facts, numbers, or scientific hypotheses needs to be communicated without losing trust and credibility. This is an empirically…